Wiggins reached 15,000 career points during his efficient performance, while Norman Powell added 25 points for the Heat. Miami outscored Memphis 39-26 in the third quarter to pull away after leading by five at halftime.
The Heat committed 18 turnovers but finished with 36 assists. Memphis was without Ja Morant (left elbow sprain) for the 13th consecutive game. Scotty Pippen Jr. and Myron Gardner were ejected after a late-game altercation.