A short-corner routine led to Sørloth's first goal, as Matteo Ruggeri's cross found the striker who confidently side-footed past Simon Mignolet. The Norwegian international then sealed the win with another close-range finish after Antoine Griezmann and Ademola Lookman combined down the left flank.
Atletico's victory means they will face either Liverpool or Tottenham Hotspur in the last-16 draw scheduled for Friday, with the Spanish side firmly in control after establishing a commanding lead.